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Publications

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Book "From Basic Neuroscience to Clinical Neurology" Part 1 | Part 2
Meetings organized by Andrej A. Romanovsky and their proceedings
Journal Temperature

Publications by year: 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 | 2014 | 2013 | 2012 | 2011 | 2010 | 2009 | 2008 | 2007 | 2006 | 2005 | 2004 | 2003 | 2002 | 2001 | 2000 | 1999 | 1998 | 1997 | 1996 | 1995 | 1994 | 1993 | 1992 | 1990 | 1988 | 1986 | 1985

 

  Cell Cycle cover J Neurosci cover Temperature cover Handb Clin Neurol cover 1 Handb Clin Neurol cover 2  


What is the impact?

2023

Vizin RCL, Almeida MC, Soriano RN, Romanovsky AA. Selection of preferred thermal environment and cold-avoidance responses in rats rely on signals transduced by the dorsal portion of the lateral funiculus of the spinal cord. Temperature 10 (1): 121-135, 2023. PDF is coming

Garami A, Steiner AA, Pakai E, Wanner SP, Almeida MC, Keringer P, Oliveira DL, Nakamura K, Morrison SF, Romanovsky AA. The neural pathway of the hyperthermic response to antagonists of the transient receptor potential vanilloid-1 channel. Temperature 10 (1): 136-154, 2023. PDF

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2022

Keringer P, Furedi N, Gaszner B, Miko A, Pakai E, Fekete K, Olah E, Kelava L, Romanovsky AA, Rumbus Z, Garami A. The hyperthermic effect of central cholecystokinin is mediated by the cyclooxygenase-2 pathway. Am J Physiol Endocrinol Metab 322: E10-E23, 2022. PDF

Romanovsky AA. Papers published by the journal Temperature are cited more often than those published by more prestigious journals. Temperature 9 (1): 1-7, 2022. PDF

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2021

Olah E, Poto L, Rumbus Z, Pakai E, Romanovsky AA, Hegyi P, Garami A. POLAR study revisited: Therapeutic hypothermia in severe brain trauma should not be abandoned. J Neurotrauma 38: 2772-2776, 2021. PDF

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2020

Garami A, Shimansky YP, Rumbus Z, Vizin RCL, Farkas N, Hegyi J, Szakacs Z, Solymar M, Csenkey A, Chiche DA, Kapil R, Kyle DJ, Van Horn WD, Hegyi P, Romanovsky AA. Hyperthermia induced by transient receptor potential vanilloid-1 (TRPV1) antagonists in human clinical trials: Insights from mathematical modeling and meta-analysis. Pharmacol Ther, 208:107474, 2020. PDF

Romanovsky AA. Terrestrial warming and cooling: Either or both? Temperature 7: 215-216, 2020. PDF

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2019

Steiner AA, Romanovsky AA. Energy trade-offs in host defense: immunology meets physiology. Trends Endocrinol Metabol 30: 875-878, 2019. PDF

Ishikawa DT, Vizin RCL, de Souza CO, Carrettiero DC, Romanovsky AA, Almeida MC. Camphor, applied epidermally to the back, causes snout- and  chest-grooming in rats: A response mediated by cutaneous TRP channels. Pharmaceuticals 12: 24, 2019. PDF

Patrone LGA, Duarte JB, Bicego KC, Steiner AA, Romanovsky AA, Gargaglioni LH. TRPV1 inhibits the ventilatory response to hypoxia in adult rats, but not the CO2-drive to breathe. Pharmaceuticals 12: 19, 2019. PDF

Csenkey A, Jozsa G, Gede N, Pakai E, Tinusz B, Rumbus Z, Lukacs A, Gyongyi Z, Hamar P, Sepp R, Romanovsky AA, Hegyi P, Vajda P, Garami A. Systemic antibiotic prophylaxis does not affect infectious complications in pediatric burn injury: a meta-analysis. PLoS One 14(9): e0223063, 2019. PDF

Sajadi MM, Romanovsky AA. Chapter 55. Temperature regulation and the pathogenesis of fever. In: Mandell, Douglas, and Bennett's Principles and Practice of Infectious Diseases, ed. by Bennett JE, Dolin R, Blaser MJ, 9th ed. Elsevier, Philadelphia, PA, 2019, vol. 1, p. 777-789. Request reprint

Romanovsky AA (inventor). Novel treatment for hot flushes. International Patent Application No. PCT/US2018/040902. WO2019/010293 A1. Publication date: 10 January 2019. English | French

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2018

Romanovsky AA (Ed.). Thermoregulation: From Basic Neuroscience to Clinical Neurology. Part 1, 1st ed. Handbook of Clinical Neurology Series, vol. 156. Elsevier, 2018. Elsevier | Amazon | Review in Temperature

Romanovsky AA (Ed.). Thermoregulation: From Basic Neuroscience to Clinical Neurology. Part 2, 1st ed. Handbook of Clinical Neurology Series, vol. 157. Elsevier, 2018. Elsevier | Amazon | Review in Temperature

Romanovsky AA. The thermoregulation system and how it works. Handb Clin Neurol 156: 3-43, 2018. PDF

Garami A, Steiner AA, Romanovsky AA. Fever and hypothermia in systemic inflammation. Handb Clin Neurol 157: 565-597, 2018. PDF

Garami A, Pakai E, McDonald HA, Reilly RM, Gomtsyan A, Corrigan JJ, Pinter E, Zhu DXD, Lehto SG, Gavva NR, Kym PR, Romanovsky AA. TRPV1 antagonists that cause hypothermia, instead of hyperthermia, in rodents: Compounds' pharmacological profiles, in vivo targets, thermoeffectors recruited and implications for drug development. Acta Physiol 223: e13038, 2018. PDF | Comment in Acta Physiol

Zaretsky DV, Romanovsky AA, Zaretskaia MV, Molkov YI. Tissue oxidative metabolism can increase the difference between local temperature and arterial blood temperature by up to 1.3°C: Implications for brain, brown adipose tissue, and muscle physiology. Temperature 5: 22-35, 2018. PDF | Cover

Olah E, Poto L, Hegyi P, Szabo I, Hartmann P, Solymar M, Petervari E, Balasko M, Habon T, Rumbus Z, Tenk J, Rostas I, Weinberg J, Romanovsky AA, Garami A. Therapeutic whole-body hypothermia reduces mortality in severe traumatic brain injury if the cooling index is sufficiently high: meta-analyses of the effect of single cooling parameters and their integrated measure. J Neurotrauma 35: 2407-2417, 2018. PubMed | Request reprint

Patwardhan A, Porreca F, Schmidt WK, Romanovsky AA. The opioid crisis and … reconsidering the use of drugs that affect body temperature. Temperature 5: 1-3, 2018. PDF

Garami A, Ibrahim M, Gilbraith K, Khanna R, Pakai E, Miko A, Pinter E, Romanovsky AA, Porreca F, Patwardhan AM. In reply. Anesthesiology 129: 378-379, 2018. PubMed | Request reprint

Garami A, Imeri L, Madden CJ, Steiner AA, Romanovsky AA. Preface. Hand Clin Neurol 156: ix, 2018. (Also reprinted as Hand Clin Neurol 157: ix, 2018.) Request reprint

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2017

Wanner SP, Almeida MC, Shimansky YP, Oliveira DL, Eales JR, Coimbra CC, Romanovsky AA. Cold-induced thermogenesis and inflammation-associated cold-seeking behavior are represented by different dorsomedial hypothalamic sites: a three-dimensional functional topography study in conscious rats. J Neurosci 37: 6956-6971, 2017. PDF | Erratum

Garami A, Ibrahim M, Gilbraith K, Khanna R, Pakai E, Miko A, Pinter E, Romanovsky AA, Porreca F, Patwardhan AM. Transient receptor potential vanilloid 1 antagonists prevent anesthesia-induced hypothermia and decrease postincisional opioid dose requirements in rodents. Anesthesiology 127: 813-823, 2017. PubMed | Request reprint | Letter | Repy

Meyer CW, Ootsuka Y, Romanovsky AA. Body temperature measurements for metabolic phenotyping in mice. Front Physiol 8: 520, 2017. PDF

Patwardhan A, Porreca F, Romanovsky AA (inventors). Compositions and methods for treatment, amelioration, and prevention of anesthesia-induced hypothermia. International Patent Application No. PCT/US2016/067825. WO2017/112693 A1.Publication date: 29 June 2017. English | French

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2016

Romanovsky AA. Education and peace go together; plus the best 2015 papers of the journal Temperature (Editorial). Temperature 3: 499-501, 2016. PDF | Letter

Romanovsky AA. Award-winning papers published in Temperature in 2014 (Editorial). Temperature 3: 8-10, 2016. PDF | Letter

Romanovsky AA. Pungency: A reason for the sluggish expansion of hot spicy foods from the tropics (Reply). Temperature 3: 56-58, 2016. PDF

Romanovsky AA. Solving a riparian puzzle: one tree farmer's experience (Popular article). Northwest Woodlands 32(1): 24-27, 2016. PDF

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2015

Pakai E, Garami A, Nucci TB, Ivanov AI, Romanovsky AA. Hyperbilirubinemia exaggerates endotoxin-induced hypothermia. Cell Cycle 14: 1260-1267, 2015. PDF

Steiner AA, Romanovsky AA. Platelet-activating factor is a potent pyrogen and cryogen, but it does not mediate lipopolysaccharide fever or hypothermia. Temperature 2: 535-542, 2015. PDF | Comment in Temperature

Garami A, Romanovsky AA. The transient receptor potential vanilloid-4 channel: detecting body temperatures that drive defences against mild warmth (Viewpoint). Acta Physiol 214: 154-156, 2015. PubMed | Request reprint

Drew KL, Romanovsky AA, Stephen TKL, Tupone D, Williams RH. Future approaches to therapeutic hypothermia: a symposium report. Temperature 2: 168-171, 2015. PDF

Carvalho F, Kiyatkin EA, Rusyniak DE, Romanovsky AA. Temperature in the spotlight of drug abuse research (Editorial). Temperature 2: 27-28, 2015. PDF

Romanovsky AA. Protecting western redcedar from deer browsing-with a passing reference to TRP channels (Editorial). Temperature 2: 142-149, 2015. PDF | Letter 1 | Letter 2 | Letter 3 | Letter 4 | Letter 5 | Letter 6 | Letter 7 | Reply

Romanovsky AA. A Valentine’s Day bouquet for Temperature readers: Pleasing with prizes, searching for the right words, and keeping things mysterious (Editorial). Temperature 2: 17-21, 2015. PDF | Letter

Romanovsky AA. The cock, the Academy, and the best scientific journal in the world (Editorial). Temperature 2: 435-438, 2015. PDF

Romanovsky AA. Which is the correct answer to the Mpemba puzzle (Reply)? Temperature 2: 63-64, 2015. PDF

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2014

De Oliveira C, Garami A, Lehto SG, Pakai E, Tekus V, Pohoczky K, Youngblood BD, Wang W, Kort ME, Kym PR, Pinter E, Gavva NR, Romanovsky AA. Transient receptor potential channel ankyrin-1 is not a cold sensor for autonomic thermoregulation in rodents. J Neurosci 34: 4445-4452, 2014. PDF | Comment in Pain Res Forum

Romanovsky AA. Skin temperature: its role in thermoregulation. Acta Physiol 210, 498–507, 2014. PDF

Ngampramuan S, Cerri M, Del Vecchio F, Corrigan JJ, Kamphee A, Dragic AS, Rudd JA, Romanovsky AA, Nalivaiko E. Thermoregulatory correlates of nausea in rats and musk shrews. Oncotarget 5: 1565-1575, 2014. PDF

Romanovsky AA. New research journals are needed and can compete with titans (Editorial). Temperature 1: 1-5, 2014. PDF | Letter | Reply

Romanovsky AA. Standing on the shoulders of giants (Editorial). Temperature 1: 71-75, 2014. PDF | Letter | Reply

Székely M, Romanovsky AA. Szilárd Donhoffer, mastermind of the study demonstrating how cold prevented death of protein deficiency (Reply). Temperature 1: 99-100, 2014. PDF

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2013

Wanner SP, Yoshida K, Kulchitsky VA, Ivanov AI, Kanosue K, Romanovsky AA. Lipopolysaccharide-induced neuronal activation in the paraventricular and dorsomedial hypothalamus depends on ambient temperature. PLoS One 8: e75733, 2013. PDF

Rance NE, Dacks PA, Mittelman-Smith MA, Romanovsky AA, Krajewski-Hall SJ. Modulation of body temperature and LH secretion by hypothalamic KNDy (kisspeptin, neurokinin B and dynorphin) neurons: A novel hypothesis on the mechanism of hot flushes. Front Neuroendocrinol 34: 211-227, 2013. PubMed | Request reprint

Deuis JR, Zimmermann K, Romanovsky AA, Possani LD, Cabot PJ, Lewis RJ, Vetter I. An animal model of oxaliplatin-induced cold allodynia reveals a crucial role for Nav1.6 in peripheral pain pathways. Pain 154: 1749-1757, 2013. PubMed | Request reprint

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2012

Almeida MC, Hew-Butler T, Soriano RN, Rao S, Wang W, Wang J, Tamayo N, Oliveira DL, Nucci TB, Aryal P, Garami A, Bautista D, Gavva NR, Romanovsky AA. Pharmacological blockade of the cold receptor TRPM8 attenuates autonomic and behavioral cold defenses and decreases deep body temperature. J Neurosci 32: 2086-2099, 2012. PDF | Supplemental data | Comment in Scientific American

Saper CB, Romanovsky AA, Scammell TE. Neural circuitry engaged by prostaglandins during the sickness syndrome. Nat Neurosci 15: 1088-1095, 2012. Author's copy | Request final PDF

Wanner SP, Garami A, Pakai E, Oliveira DL, Gavva NR, Coimbra CC, Romanovsky AA. Aging reverses the role of the transient receptor potential vanilloid-1 channel in systemic inflammation from anti-inflammatory to proinflammatory. Cell Cycle 11: 343-349, 2012. PDF | Comment in Cell Cycle

Liu E, Lewis K, Al-Saffar H, Krall CM, Singh A, Kulchitsky VA, Corrigan JJ, Simons CT, Petersen SR, Musteata FM, Bakshi CS, Romanovsky AA, Sellati TJ, Steiner AA. Naturally occurring hypothermia is more advantageous than fever in severe forms of lipopolysaccharide- and Escherichia coli-induced systemic inflammation. Am J Physiol 302: R1372-R1383, 2012. PDF

Romanovsky AA. The inflammatory reflex: the current model should be revised (Viewpoint). Exp Physiol 97: 1178-1179, 2012. PDF

Romanovsky AA. Revised h index for biomedical research (Editorial). Cell Cycle 11, 4118-4121, 2012. PDF

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2011

Garami A, Pakai E, Oliveira DL, Steiner AA, Wanner SP, Almeida MC, Lesnikov VA, Gavva NR, Romanovsky AA. Thermoregulatory phenotype of the Trpv1 knockout mouse: thermoeffector dysbalance with hyperkinesis. J Neurosci 31: 1721-1733, 2011. PDF | Supplemental data | Cover | Auto-perspective in Aging | Reviewed by Faculty of 1000

Wanner SP, Garami A, Romanovsky AA. Hyperactive when young, hypoactive and overweight when aged: Connecting the dots in the story about locomotor activity, body mass, and aging in Trpv1 knockout mice. Aging 3: 450-454, 2011. PDF

Steiner AA, Molchanova AY, Dogan MD, Patel S, Pétervári E, Balaskó M, Wanner SP, Eales J, Oliveira DL, Gavva NR, Almeida MC, Székely M, Romanovsky AA. The hypothermic response to bacterial lipopolysaccharide critically depends on brain CB1, but not CB2 or TRPV1, receptors. J Physiol 589: 2415-2431, 2011. PDF

Romanovsky AA. Selective brain cooling in humans: we don’t fly, but we walk just fine (Letter). J Appl Physiol 110: 577, 2011. PDF

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2010

Garami A, Shimansky YP, Pakai E, Oliveira DL, Gavva NR, Romanovsky AA. Contributions of different modes of TRPV1 activation to TRPV1 antagonist-induced hyperthermia. J Neurosci 30: 1435-1440, 2010. PDF

Romanovsky AA, Garami A. Prostaglandin riddles in energy metabolism: E is for excess, D is for depletion (Editorial). Am J Physiol 298: R1509-R1511, 2010. PDF

Ferro TN, Goslar PW, Romanovsky AA, Petersen SR. Smoking in trauma patients: the effects on the incidence of sepsis, respiratory failure, organ failure and mortality. J Trauma 69: 308-312, 2010. PubMed | Request reprint | Comment in J Trauma (published with article; pp. 311-312)

Garami A, Almeida MC, Nucci TB, Hew-Butler T, Soriano RN, Pakai E, Nakamura K, Morrison SF, Romanovsky AA. Chapter 14. The TRPV1 channel in normal thermoregulation: What have we learned from experiments using different tools? In: Vanilloid Receptor TRPV1 in Drug Discovery: Targeting Pain and Other Pathological Disorders, ed. by Gomtsyan A, Faltynek CR. Hoboken, NJ: John Wiley & Sons, 2010, p. 351-402. Request reprint

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2009

Romanovsky AA, Almeida MC, Garami A, Steiner AA, Norman MH, Morrison SF, Nakamura K, Burmeister JJ, Nucci TB. The transient receptor potential vanilloid-1 channel: a thermosensor it is not. Pharmacol Rev 61: 228-261, 2009. PDF | Comment in Pharmacol Rev

Steiner AA, Hunter JC, Phipps SM, Nucci TB, Oliveira DL, Roberts JL, Scheck AC, Simmons DL, Romanovsky AA. Cyclooxygenase-1 or -2 — which one mediates lipopolysaccharide-induced hypothermia? Am J Physiol 297: R485-R494, 2009. PDF

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2008

Gavva NR, Treanor JJS, Garami A, Fang L, Surapaneni S, Akrami A, Alvarez F, Bak A, Darling M, Gore A, Jang GR, Kesslak JP, Ni L, Norman MH, Palluconi G, Rose MJ, Salfi M, Tan E, Romanovsky AA, Banfield C, Davar G. Pharmacological blockade of the vanilloid receptor TRPV1 elicits marked hyperthermia in humans. Pain 136: 202-210, 2008. Editorial in Pain (PubMed) | Reviewed by Faculty of 1000 | Request reprint

Steiner AA, Oliveira DL, Roberts JL, Petersen SR, Romanovsky AA. Nicotine administration and withdrawal affect survival in systemic inflammation models. J Appl Physiol 105: 1028-1034, 2008. PDF | Editorial in J Appl Physiol | Highlight in Physiology

Ootsuka Y, Blessing WW, Steiner AA, Romanovsky AA. Fever response to intravenous prostaglandin E2 is mediated by the brain but does not require afferent vagal signaling. Am J Physiol 294: R1294-R1303, 2008. PDF

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2007

Romanovsky AA. Thermoregulation: some concepts have changed. Functional architecture of the thermoregulatory system. Am J Physiol 292: R37-R46, 2007. PDF

Steiner AA, Turek VF, Almeida MC, Burmeister JJ, Oliveira DL, Roberts JL, Bannon AW, Norman MH, Louis J-C, Treanor JJS, Gavva NR, Romanovsky AA. Nonthermal activation of transient receptor potential vanilloid-1 channels in abdominal viscera tonically inhibits autonomic cold-defense effectors. J Neurosci 27: 7459-7468, 2007. PDF | Comment in Curr Biol (PubMed) | Reviewed by Faculty of 1000

Steiner AA, Romanovsky AA. Leptin: At the crossroads of energy balance and systemic inflammation. Prog Lipid Res 46: 89-107, 2007. Author manuscript | Request reprint

Romanovsky AA. Chapter 23. Temperature regulation. In: Lecture Notes on Human Physiology, 5th edition, ed. by Petersen O. Oxford, UK: Blackwell, 2007, p. 603-615. Request reprint

Aronoff DM, Romanovsky AA. Eicosanoids in non-febrile thermoregulation. Prog Brain Res 162: 15-25, 2007. PubMed | Request reprint

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2006

Steiner AA, Ivanov AI, Serrats J, Hosokawa H, Phayre AN, Robbins JR, Roberts JL, Kobayashi S, Matsumura K, Sawchenko PE, Romanovsky AA. Cellular and molecular bases of the initiation of fever. PLoS Biol 4: e284, 2006. PDF | Synopsis in PLoS Biol | Autocommentary in Cell Cycle

Steiner AA, Chakravarty S, Rudaya AY, Herkenham M, Romanovsky AA. Bacterial lipopolysaccharide fever is initiated via Toll-like receptor 4 on hematopoietic cells. Blood 107: 4000-4002, 2006. PDF | Autocommentary in Cell Cycle

Almeida MC, Steiner AA, Branco LGS, Romanovsky AA. Neural substrate of cold-seeking behavior in endotoxin shock. PLoS One 1: e1, 2006. PDF | Reviewed by Faculty of 1000

Romanovsky AA, Steiner AA, Matsumura K. Cells that trigger fever. Cell Cycle 5: 2195-2197, 2006. PDF | Cover

Almeida MC, Steiner AA, Branco LGS, Romanovsky AA. Cold-seeking behavior as a thermoregulatory strategy in systemic inflammation. Eur J Neurosci 23: 3359-3367, 2006. PubMed | Request reprint

Ivanov AI, Romanovsky AA. Putative dual role of ephrin-Eph receptor interactions in inflammation. IUBMB Life 58: 389-394, 2006. PubMed | Request reprint

Romanovsky AA, Ivanov AI, Petersen SR. Microsomal prostaglandin E synthase-1, ephrins, and ephrin kinases as suspected targets in arthritis: exposed by “criminal profiling”. Ann N Y Acad Sci 1069: 183-194, 2006. PubMed | Request reprint

Steiner AA, Roth J, Romanovsky AA. Hot, cool, and vibrant (Preface). J Therm Biol 31: 1-3, 2006. Request reprint

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2005

Romanovsky AA, Almeida MC, Aronoff DM, Ivanov AI, Konsman JP, Steiner AA, Turek VF. Fever and hypothermia in systemic inflammation: recent discoveries and revisions. Front Biosci 10: 2193-2216, 2005. PDF

Rudaya AY, Steiner AA, Robbins JR, Dragic AS, Romanovsky AA. Thermoregulatory responses to lipopolysaccharide in the mouse: dependence on the dose and ambient temperature. Am J Physiol 289: R1244-R1252, 2005. PDF

Steiner AA, Rudaya AY, Robbins JR, Dragic AS, Langenbach R, Romanovsky AA. Expanding the febrigenic role of cyclooxygenase-2 to the previously overlooked responses. Am J Physiol 289: R1253-R1257, 2005. PDF

Steiner AA, Chakravarty S, Robbins JR, Dragic AS, Pan J, Herkenham M, Romanovsky AA. Thermoregulatory responses of rats to conventional preparations of lipopolysaccharide are caused by lipopolysaccharide per se — not by lipoprotein contaminants. Am J Physiol 289: R348-R352, 2005. PDF

Ivanov AI, Steiner AA, Scheck AC, Romanovsky AA. Expression of Eph receptors and their ligands, ephrins, during lipopolysaccharide fever in rats. Physiol Genomics 21: 152-160, 2005. PDF

Ivanov AI, Steiner AA, Patel S, Rudaya AY, Romanovsky AA. Albumin is not an irreplaceable carrier for amphipathic mediators of thermoregulatory responses to lipopolysaccharide: compensatory role of α1-acid glycoprotein. Am J Physiol 288: R872-R878, 2005. PDF

Romanovsky AA. Vioxx, Celebrex, Bextra....Do we have a new target for anti-inflammatory and antipyretic therapy (Editorial)? Am J Physiol 288: R1098-R1099, 2005. PDF

Romanovsky AA. Reply. Am J Physiol 289: R281-R282, 2005. PDF

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2004

Ivanov AI, Romanovsky AA. Prostaglandin E2 as a mediator of fever: synthesis and catabolism. Front Biosci 9: 1977-1993, 2004. PDF

Steiner AA, Dogan MD, Ivanov AI, Patel S, Rudaya AY, Jennings DH, Orchinik M, Pace TWW, O'Connor KA, Watkins LR, Romanovsky AA. A new function of the leptin receptor: mediation of the recovery from lipopolysaccharide-induced hypothermia. FASEB J 18: 1949-1951, 2004. PDF (short version; use for citation) | PDF (full online version for additional details)

Dogan MD, Patel S, Rudaya AY, Steiner AA, Szekely M, Romanovsky AA. Lipopolysaccharide fever is initiated via a capsaicin-sensitive mechanism independent of the subtype-1 vanilloid receptor. Br J Pharmacol 143: 1023-1032, 2004. PDF

Steiner AA, Rudaya AY, Ivanov AI, Romanovsky AA. Febrigenic signaling to the brain does not involve nitric oxide. Br J Pharmacol 141: 1204-1213, 2004. PDF

Romanovsky AA. Do fever and anapyrexia exist? Analysis of set point-based definitions. Am J Physiol 287: R992-R995, 2004. PDF | Letter and reply in Am J Physiol

Romanovsky AA. Anorexia: the toll for lipopolysaccharide recognition (Editorial). Am J Physiol 287: R274-R275, 2004. PDF

Romanovsky AA. Signaling the brain in the early sickness syndrome: are sensory nerves involved? Front Biosci 9: 494-504, 2004. PDF

Szelenyi Z, Szekely M, Hummel Z, Balasko M, Romanovsky AA, Petervari E. Cholecystokinin: possible mediator of fever and hypothermia. Front Biosci 9: 301-308, 2004. PDF

Romanovsky AA, Steiner AA, Branco LGS, Jansky L, Gourine VN. Arginine vasopressin in fever: a still unsolved puzzle. J Therm Biol 29: 407-411, 2004. Request reprint

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2003

Ivanov AI, Patel S, Kulchitsky VA, Romanovsky AA. Platelet-activating factor: a previously unrecognized mediator of fever. J Physiol 553: 221-228, 2003. PDF | Comment in Nat Rev Neurosci

Ivanov AI, Kulchitsky VA, Romanovsky AA. Role for the cholecystokinin-A receptor in fever: a study of a mutant rat strain and a pharmacological analysis. J Physiol 547: 941-949, 2003. PDF

Ivanov AI, Scheck AC, Romanovsky AA. Expression of genes controlling transport and catabolism of prostaglandin E2 in lipopolysaccharide fever. Am J Physiol 284: R698-R706, 2003. PDF

Romanovsky AA, Sugimoto N, Simons CT, Hunter WS. The organum vasculosum laminae terminalis in immune-to-brain febrigenic signaling: a reappraisal of lesion experiments. Am J Physiol 285: R420-R428, 2003. PDF

Romanovsky AA, Petersen SR. The spleen: another mystery about its function (Editorial). Am J Physiol 284: R1378-R1379, 2003. PDF

Dogan MD, Kulchitsky VA, Patel S, Petervari E, Szekely M, Romanovsky AA. Bilateral splanchnicotomy does not affect lipopolysaccharide-induced fever in rats. Brain Res 993: 227-229, 2003. PubMed | Request reprint

Ivanov AI, Romanovsky AA. Near-term suppression of fever: inhibited synthesis or accelerated catabolism of prostaglandin E2 (Letter)? Am J Physiol 284: R860- R865, 2003. PDF (letter and replies)

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2002

Romanovsky AA, Ivanov AI, Shimansky YP. Selected contribution: Ambient temperature for experiments in rats: a new method for determining the zone of thermal neutrality. J Appl Physiol 92: 2667-2679, 2002. PDF | Comment in J Appl Physiol

Ivanov AI, Pero RS, Scheck AC, Romanovsky AA. Prostaglandin E2-synthesizing enzymes in fever: differential transcriptional regulation. Am J Physiol 283: R1104-R1117, 2002. PDF

Ivanov AI, Romanovsky AA. Fever responses of Zucker rats with and without fatty mutation of the leptin receptor. Am J Physiol 282: R311-R316, 2002. PDF

Romanovsky AA. Las fibras nerviosas sensitivas intervienen en la fase febril temprana (in Spanish). SIIC En Internet 2002. Restricted at journal

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2001

Ivanov AI, Kulchitsky VA, Romanovsky AA. Does obesity affect febrile responsiveness? Int J Obes Relat Metab Disord 25: 586-589, 2001. PDF

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2000

Romanovsky AA, Ivanov AI, Szekely M. Neural route of pyrogen signaling to the brain. Clin Infect Dis 31: S162-S167, 2000. PDF

Romanovsky AA. Thermoregulatory manifestations of systemic inflammation: lessons from vagotomy. Auton Neurosci 85: 39-48, 2000. PubMed | Request reprint

Szekely M, Balasko M, Kulchitsky VA, Simons CT, Ivanov AI, Romanovsky AA. Multiple neural mechanisms of fever. Auton Neurosci 85: 78-82, 2000. PubMed | Request reprint

Ivanov AI, Kulchitsky VA, Sugimoto N, Simons CT, Romanovsky AA. Does the formation of lipopolysaccharide tolerance require intact vagal innervation of the liver? Auton Neurosci 85: 111-118, 2000. PubMed | Request reprint

Romanovsky AA, Ivanov AI, Lenczowski MJP, Kulchitsky VA, Van Dam A-M, Poole S, Homer LD, Tilders FJH. Lipopolysaccharide transport from the peritoneal cavity to the blood: is it controlled by the vagus nerve? Auton Neurosci 85: 133-140, 2000. PubMed | Request reprint

Romanovsky AA. Six blind men and the manifold vagus (Preface). Auton Neurosci 85: vii-ix, 2000. Request reprint

Romanovsky AA, Blatteis CM. Heat defense control in an experimental heat disorder. Int J Biometeorol 43: 172-175, 2000. PubMed | Request reprint

Romanovsky AA, Ivanov AI, Berthoud HR, Kulchitsky VA. Are vagal efferents involved in the fever response to intraperitoneal lipopolysaccharide? J Therm Biol 25: 65-70, 2000. Restricted at journal | Request reprint

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1999

Romanovsky AA, Ivanov AI, Karman EK. Blood-borne, albumin-bound prostaglandin E2 may be involved in fever. Am J Physiol 276: R1840-R1844, 1999. PDF

Sugimoto N, Simons CT, Romanovsky AA. Vagotomy does not affect thermal responsiveness to intrabrain prostaglandin E2 and cholecystokinin octapeptide. Brain Res 844: 157-163, 1999. PubMed | Request reprint

Romanovsky AA. Paracelsus on wound treatment (Letter). Lancet 354: 1910, 1999. PubMed | Request reprint

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1998

Romanovsky AA, Simons CT, Kulchitsky VA. “Biphasic” fevers often consist of more than two phases. Am J Physiol 275: R323-R331, 1998. PDF

Simons CT, Kulchitsky VA, Sugimoto N, Homer LD, Szekely M, Romanovsky AA. Signaling the brain in systemic inflammation: which vagal branch is involved in fever genesis? Am J Physiol 275: R63-R68, 1998. PDF

Romanovsky AA, Kulchitsky VA, Simons CT, Sugimoto N. Methodology of fever research: why are polyphasic fevers often thought to be biphasic? Am J Physiol 275: R332-R338, 1998. PDF

Romanovsky AA, Szekely M. Fever and hypothermia: two adaptive thermoregulatory responses to systemic inflammation. Med Hypotheses 50: 219-226, 1998. PubMed | Request reprint

Romanovsky AA. Febrile nonresponsiveness of vagotomized animals: is it due to endotoxin translocation from the gut and tolerance (Letter)? Am J Physiol 275: R933-R934, 1998. PDF (letter and reply)

Romanovsky AA, Blatteis CM. Pathophysiology of opioids in hyperthermic states. Prog Brain Res 115: 111-127, 1998. PubMed | Request reprint

Szekely M, Romanovsky AA. Pyretic and antipyretic signals within and without fever: a possible interplay. Med Hypotheses 50: 213-218, 1998. PubMed | Request reprint

Romanovsky AA. Mini-Symposium on Clinical Thermophysiology: New Hypotheses and Emerging Concepts (Preface). Med Hypotheses 50: 183-184, 1998. Request reprint

Romanovsky AA, Simons CT, Kulchitsky VA, Sugimoto N, Szekely M. Vagus nerve in fever: recent developments. Ann N Y Acad Sci 856: 298-299, 1998. PubMed | Request reprint

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1997

Romanovsky AA, Simons CT, Szekely M, Kulchitsky VA. The vagus nerve in the thermoregulatory response to systemic inflammation. Am J Physiol 273: R407-R413, 1997. Toll-free link | Downloading help

Romanovsky AA, Kulchitsky VA, Simons CT, Sugimoto N, Szekely M. Cold defense mechanisms in vagotomized rats. Am J Physiol 273: R784-R789, 1997. Toll-free link | Downloading help

Romanovsky AA, Kulchitsky VA, Simons CT, Sugimoto N, Szekely M. Febrile responsiveness of vagotomized rats is suppressed even in the absence of malnutrition. Am J Physiol 273: R777-R783, 1997. Toll-free link | Downloading help

Romanovsky AA, Karman YK. Posthemorrhagic antipyresis: what stage of fever genesis is affected? J Appl Physiol 83: 359-365, 1997. PDF

Romanovsky AA, Quint PA, Benikova Y, Kiesow LA. A difference of 5 degrees C between the ear and rectal temperatures in a febrile patient. Am J Emerg Med 15: 383-385, 1997. PubMed | Request reprint

Romanovsky AA, Shido O, Sakurada S, Sugimoto N, Nagasaka T. Endotoxin shock-associated hypothermia. How and why does it occur? Ann N Y Acad Sci 813: 733-737, 1997. PubMed | Request reprint

Romanovsky AA, Blatteis CM. Naltrexone modifies thermoregulatory symptoms and lessens the severity of heat stroke in guinea pigs. Ann N Y Acad Sci 813: 548-552, 1997. PubMed | Request reprint

Romanovsky AA, Kulchitsky VA, Akulich NV, Koulchitsky SV, Simons CT, Sessler DI, Gourine VN. The two phases of biphasic fever — two different strategies of fighting infection? Ann N Y Acad Sci 813: 485-490, 1997. PubMed | Request reprint

Romanovsky AA, Simons CT, Szekely M, Kulchitsky VA. Febrile irresponsiveness of vagotomized rats to a pyrogenic signal. Non-sensing brain or non-heating body? Ann N Y Acad Sci 813: 437-444, 1997. PubMed | Request reprint

Szekely M, Balasko M, Romanovsky AA. Peripheral neural inputs. Their role in fever development. Ann N Y Acad Sci 813: 427-434, 1997. PubMed | Request reprint

Szekely M, Simons CT, Kulchitsky VA, Romanovsky AA. The abdominal vagus: its presumed role in fever and non-febrile temperature regulation. In: Thermal Physiology 1997, ed. by Nielsen Johannsen B, Nielsen R. Copenhagen, Denmark: TAKI, 1997, p. 289-292. Request reprint

Kanosue K, Romanovsky AA, Hosono T, Chen X-M, Zhang Y-Z. “Set point” revisited. In: Thermal Physiology 1997, ed. by Nielsen Johannsen B, Nielsen R. Copenhagen, Denmark: TAKI, 1997, p. 39-43. Request reprint

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1996

Romanovsky AA, Kulchitsky VA, Akulich NV, Koulchitsky SV, Simons CT, Sessler DI, Gourine VN. First and second phases of biphasic fever: two sequential stages of the sickness syndrome? Am J Physiol 271: R244-R253, 1996. Toll-free link | Downloading help

Romanovsky AA, Shido O, Sakurada S, Sugimoto N, Nagasaka T. Endotoxin shock: thermoregulatory mechanisms. Am J Physiol 270: R693-R703, 1996. Toll-free link | Downloading help

Romanovsky AA, Blatteis CM. Heat stroke: opioid-mediated mechanisms. J Appl Physiol 81: 2565-2570, 1996. PDF

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1995

Romanovsky AA, Blatteis CM. Biphasic fever: what triggers the second temperature rise? Am J Physiol 269: R280-R286, 1995. Toll-free link | Downloading help

Shido O, Romanovsky AA, Sakurada S, Sugimoto N, Nagasaka T. Behavioral and autonomic thermoregulation of rats injected with a large dose of LPS. In: Body Temperature and Metabolism, ed. by Nagasaka T, Milton AS. Tokyo, Japan: IPEC, 1995, p. 71-73. Request reprint

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1994

Romanovsky AA, Shido O, Ungar AL, Blatteis CM. Peripheral naloxone attenuates lipopolysaccharide fever in guinea pigs by an action outside the blood-brain barrier. Am J Physiol 266: R1824-R1831, 1994. Toll-free link | Downloading help

Szelenyi Z, Bartho L, Szekely M, Romanovsky AA. Cholecystokinin octapeptide (CCK-8) injected into a cerebral ventricle induces a fever-like thermoregulatory response mediated by type B CCK-receptors in the rat. Brain Res 638: 69-77, 1994. PubMed | Request reprint

Romanovsky AA, Jansky L, Gourine VN. V2-receptor-mediated hyperpyretic effect of arginine vasopressin in the ventral septal area of the rabbit brain. In: Thermal Balance in Health and Disease: Recent Basic Research and Clinical Progress, ed. by Zeisberger E, Schonbaum E, Lomax P. Basel, Switzerland: Birkhauser, 1994, p. 415-420. Request reprint

Romanovsky AA, Blatteis CM. Body temperature elevation per se induces the late phase syndrome. In: Temperature Regulation: Recent Physiological and Pharmacological Advances, ed. by Milton AS. Basel, Switzerland: Birkhauser, 1994, p. 41-46. Request reprint

Blatteis CM, Romanovsky AA. Endogenous opioids and fever. In: Thermal Balance in Health and Disease: Recent Basic Research and Clinical Progress, ed. by Zeisberger E, Schonbaum E, Lomax P. Basel, Switzerland: Birkhauser, 1994, p. 435-441. Request reprint

Blatteis CM, Shido O, Romanovsky AA. Fever and preoptic norepinephrine. In: Integrative and Cellular Aspects of Autonomic Functions: Temperature and Osmoregulation, ed. by Pleschka K, Gerstberger R. Paris, France: John Libbey Eurotext, 1994, p. 137-141. Request reprint

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1993

Shido O, Romanovsky AA, Ungar AL, Blatteis CM. Role of intrapreoptic norepinephrine in endotoxin-induced fever in guinea pigs. Am J Physiol 265: R1369-R1375, 1993. Toll-free link | Downloading help

Romanovsky AA, Shido O, Ungar AL, Blatteis CM. Genesis of biphasic thermal response to intrapreoptically microinjected clonidine. Brain Res Bull 31: 509-513, 1993. PubMed | Request reprint

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1992

Romanovskii AA, Karman EK, Gurin VN. The fever reaction of the polecat Mustela putorius x Mustela putorius furo to a bacterial pyrogen: the hypo- and hyperthermic phases (in Russian). Zh Evol Biokhim Fiziol 28: 678-684, 1992. PubMed | PDF

Szelenyi Z, Szekely M, Romanovskii AA. The central thermoregulatory action of cholecystokinin-8 and prostaglandin E1 (in Russian). Fiziol Zh SSSR Im | M Sechenova 78: 94-101, 1992. PubMed | PDF

Romanovsky AA. Thermoregulation during fever. In: Problems of Thermoregulation and Temperature Adaptation, ed. by Popova NK. Novosibirsk, Russia: Institute of Cytology and Genetics, 1992, p. 108-117 (in Russian). PDF

Romanovsky AA. Russian thermophysiology today. Physiologist 35: 137-142, 1992. PDF

Romanovsky AA. Light at the end of the tunnel (Letter)? Nature 356: 100, 1992. Restricted at journal | Request reprint | Comment in Bull Atom Sci

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1990

Jansky L, Vybiral S, Romanovsky AA, Gourine VN. The mode of neuropeptide action on thermoregulation. In: Neuropeptides and Thermoregulation, ed. by Gourine VN. Minsk, Belarus: Navuka i Tekhnika, 1990, p. 9-31 (in Russian). English summary | PDF

Gourine VN, Romanovsky  AA. Role of the hormonal pool of arginine vasopressin in thermoregulation during fever. In: Neuropeptides and Thermoregulation, ed. by Gourine VN.  Minsk, Belarus: Navuka i Tekhnika, 1990, p. 31-50 (in Russian). English summary | PDF

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1988

Romanovskii AA, Grigor’ev VA. Changes in the bioelectrochemical activity of the neurosecretory hypothalamic nuclei in fever caused by endogenous pyrogen/interleukin-1 (in Russian). Fiziol Zh SSSR Im I M Sechenova 74: 1731-1737, 1988. PubMed | PDF

Romanovskii AA. Effect of the intravenous administration of arginine vasopressin on the body temperature of rabbits (in Russian). Izv Akad Nauk SSSR Biol (2): 246-250, 1988. PubMed | PDF

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1986

Romanovskii AA, Mgaloblishvili GI, Beliavskii EM, Safonova ES. Antidiuresis in fever: a possible role of vasopressin (in Russian). Patol Fiziol Eksp Ter (5): 68-71, 1986. PubMed | PDF

Mgaloblishvili GI, Romanovskii AA. Role of bacterial pyrogen in the development of antidiuresis in fever (in Russian). Patol Fiziol Eksp Ter (6): 74-77, 1986. PubMed | PDF

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1985

Romanovskii AA. Mechanisms of endogenous antipyresis (in Russian). Patol Fiziol Eksp Ter (4): 70-72, 1985. PubMed | PDF

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Photo by Alan R. Gibson.

Dust storm and rain left their touch on Alan's window. And then a bird made an impact. Photo by Alan R. Gibson.

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